Acacetin inhibits expression of matrix metalloproteinases via a MAPK ‐dependent mechanism in fibroblast‐like synoviocytes
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چکیده
منابع مشابه
Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes
It is well known that rheumatoid arthritis (RA) is an autoimmune joint disease in which fibroblast-like synoviocytes (FLSs) play a pivotal role. In this study, we investigated the anti-arthritic properties of acacetin in FLSs. The expression of matrix metalloproteinase (MMP)-1, MMP-3 and MMP-13 were investigated by quantitative RT-PCR and western blot at gene and protein levels. At the same tim...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2015
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.12564